Sodium carboxymethylcellulose is among pharmaceutical excipients that can be used to increase viscosity in topical, dental and parenteral pharmaceutical formulation, next to that it can also be used as binder as well as disintegrant in tablet formulation. Sodium Carboxymethyl Cellulose (SCMC or CMC) or Cellulose Gum is an anionic water soluble polymer; it is derived from cellulose, which is made water soluble by a chemical reaction. The water solubility is attained by presenting carboxymethyl groups along the cellulose chain, that makes hydration of the molecule possible.
Our cellulose ethers easily dissolve in cold water; the lower viscosity grades are more easily dissolved versus the high viscosity grades. Formulators achieve dissolution by slowly including the cellulosic ether polymer to water with constant mixing to completely spread the polymer and prevent heap. if the temperature is listed below a gel point. Keep in mind that HPMC and HEMC can reveal gel temperatures as low as 40 ° C; the gels will vanish after cooling down. Aqueous solutions of HEC are stable and do not gel at high or low temperatures. HEC has been used at temperatures approximately 110 ° C. The cellulose ether polymer solutions are non-Newtonian; service viscosities decrease considerably at high-shear rates. Fluid viscosities rapidly increase with an increase in the polymer concentration. In the absence of shear, viscosities can be really high, based on the pseudoplastic nature of these polymers. Because the cellulose ethers are non-ionic, they are stable at high salt focus and do not precipitate.
Cellulose ether polymers are used by the paint industry as thickening agents for waterborne paints. Cellulose ether is an absolutely multitalented chemical. Its initial material cellulose can handle different solubility buildings via etherification, resulting in a polymer that is soluble in either water or many various other organic solvents. Cellulose is the most abundant polysaccharide in the world as well as is the principal architectural component of trees and also plants. It consists of repeating D-anhydroglucose devices joined together by β-1-4-glycosidic bonds. Number 1 contains the structure of cellulose (when R=OH). Each anhydroglucose system contains a hydroxyl group at the 2, 3, and also 5 positions on the ring. On top of that, cellulose is identified by the decreasing and also non-reducing ends, which include one as well as two hydroxyl groups, respectively.
This particular makes cellulose ether very flexible and also enables it to have a wide variety of functions in various fields. Cellulose ether products are used in an entire host of applications, including construction materials, cleansing agents, food production and much more. Cellulose ether acts as a binder, safety colloid, thickener, water retention agent, film former, etc, for the production of various industrial products such as building materials, paints, paper, detergent, fabrics as well as food. In the construction industry, cellulose ether is used as a thickener as well as water retention agent. In the food industry, cellulose ether is used in confectionery, pastry shop products, nuts, lotion, creams, sweetener tablets, cheese and also tomato sauces. Our cellulose ethers are mostly used as rheology modifiers in various construction applications.
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